发明名称 |
Lipopeptide inducing T-cytotoxic lymphocytes and their use as vaccines |
摘要 |
<p>The use of a lipopeptide (I) is claimed for the immunization of humans or animals against pathogens or tumor cells, where (I) contains: (i) a peptide component having 10-40 (preferably 10-20) amino acids; (ii) at least one antigenic determinant which specifically induces cytotoxic T-lymphocytes; and (iii) one or more chains derived from N- epsilon -palmitoyl-L-lysine, coupled to the carboxy functions of the aminoacids. An Independent claim is included for a lipopeptide (I') for immunization against HIV-1 or HIV-2, comprising (I) as above in which component (i) is a fragment of an HIV-1 or HIV-2 protein.</p> |
申请公布号 |
EP1065212(A2) |
申请公布日期 |
2001.01.03 |
申请号 |
EP20000117513 |
申请日期 |
1991.12.18 |
申请人 |
INSTITUT PASTEUR DE LILLE;INSTITUT NATIONAL DE LA SANTE ET DE LA |
发明人 |
BOUTILLON, CHRISTOPHE;MARTINON, FREDERIC;SERGHERAERT, CHRISTIAN;MAGNE, REMY;GRAS-MASSE, HELENA;GOMARD, ELISABETH;TARTAR, ANDRE;LEVY, JEAN-PAUL |
分类号 |
C12N5/06;A61K38/00;A61K39/00;A61K39/21;A61P31/12;A61P37/04;C07K7/06;C07K7/08;C07K14/00;C07K14/155;C07K14/16;C07K14/705;(IPC1-7):C07K14/16;A61K47/48 |
主分类号 |
C12N5/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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