摘要 |
The invention provides pure enatiomers of 4,5-disubstituted .gamma.-butyrolactams of the general formula (see formula I) By means of the pure enantiomers of 4,5-disubstituted .gamma.-butyrolactams (I), according to the invention, it is now possible to synthesize (+)-(3R),(4S),(5S),(7R)-3-hydroxy- 5-.alpha.-hydroxybenzyl-1-methyl-4-phenyl-pyrrolidin-2-one and derivatives in the form of pure enantiomers.
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