发明名称 PURE ENANTIOMERS OF 4,5-DISUBSTITUTED .ALPHA.-BUTYROLACTAMS,PROCESS FOR THEIR PREPARATION, AND THEIR USE
摘要 The invention provides pure enatiomers of 4,5-disubstituted .gamma.-butyrolactams of the general formula (see formula I) By means of the pure enantiomers of 4,5-disubstituted .gamma.-butyrolactams (I), according to the invention, it is now possible to synthesize (+)-(3R),(4S),(5S),(7R)-3-hydroxy- 5-.alpha.-hydroxybenzyl-1-methyl-4-phenyl-pyrrolidin-2-one and derivatives in the form of pure enantiomers.
申请公布号 CA1341159(C) 申请公布日期 2001.01.02
申请号 CA19870537333 申请日期 1987.05.19
申请人 HARTWIG, WOLFGANG 发明人 HARTWIG, WOLFGANG
分类号 C07D401/04;A61K31/40;A61K31/4015;A61K31/4427;A61K31/443;A61K31/4433;A61K31/445;A61K31/47;A61K31/50;A61K31/505;A61P9/00;A61P25/28;C07D207/26;C07D207/273;C07D207/28;C07D241/08;C07D405/04;C07D409/04;(IPC1-7):C07D207/28;C07D401/00;C07D403/00;A61K31/401 主分类号 C07D401/04
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