| 摘要 |
Compounds of formulae (I) and (Ia): (see above formulas I, II) where L is a saturated or unsaturated five-membered or six-membered heterocyclic structure. The novel compounds and their physiologically tolerated salts can be used in the topical and systemic therapy and prophylaxis of precancerous conditions and carcinomas of the skin, of the mucus membranes and of the internal organs and in the topical and systemic therapy of acne, psoriasis and other dermatological disorders accompanied by pathological changes in hornification, in particular ichthyosis, Darier's disease, lichen or leucoplakia, or even against eczema, vitiligo, dry eyes and other corneo-pathias, and for the treatment of rheumatic disorders, in particular those of an inflammatory or degenerative nature. As cosmetics, these compounds can be used for the therapy of injury to the skin by light (embrittlement, creases and wrinkles due to excessive exposure to UV light or sunlight and against warts.
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