发明名称 |
Vascular endothelial growth factor (VEGF) Nucleic Acid Ligand Complexes |
摘要 |
This invention discloses a method for preparing a complex comprised of a VEGF Nucleic Acid Ligand and a Lipophilic Compound by identifying a VEGF Nucleic Acid Ligand by SELEX methodology and associating the VEGF Nucleic Acid Ligand with a Lipophilic Compound. The invention further discloses Complexes comprising one or more VEGF Nucleic Acid Ligands in association with a Lipophilic Compound. The invention further includes a Lipid construct comprising a VEGF Nucleic Acid Ligand or Complex and methods for making the same.
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申请公布号 |
US6168778(B1) |
申请公布日期 |
2001.01.02 |
申请号 |
US19970870930 |
申请日期 |
1997.06.06 |
申请人 |
NEXSTAR PHARMACEUTICALS, INC. |
发明人 |
JANJIC NEBOJSA;GOLD LARRY;SCHMIDT PAUL;VARGEESE CHANDRA |
分类号 |
A61K38/00;C07B61/00;C07H19/06;C07H19/10;C07H21/00;C07K14/00;C07K14/47;C07K14/52;C12N9/12;C12N15/10;C12N15/115;C12N15/88;C12Q1/37;C12Q1/68;C12Q1/70;F02B75/02;G01N33/531;G01N33/532;G01N33/535;G01N33/569;G01N33/68;G01N33/76;(IPC1-7):A61K31/711;A61K31/710;C12P19/34 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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地址 |
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