| 发明名称 |
Avirulent brucella and uses thereof |
| 摘要 |
The present invention discloses a novel approach to attenuating bacteria and their us as live vaccines. In particular, there is disclosed a method of attenuating bacteria by mutating bacA. The invention also discloses methods of importing compounds into cells by BacA mediated transport and methods by identifying BacA ligands. |
| 申请公布号 |
AU5731300(A) |
申请公布日期 |
2001.01.02 |
| 申请号 |
AU20000057313 |
申请日期 |
2000.06.09 |
| 申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;LOUISIANA STATE UNIVERSITY MEDICAL CENTER |
发明人 |
KRISTIN LEVIER;GRAHAM C. WALKER;ROY M. ROOP II;ROBERT W. PHILLIPS;GREGORY T. ROBERTSON |
| 分类号 |
C07K14/23;C12N1/21;C12N15/31 |
主分类号 |
C07K14/23 |
| 代理机构 |
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