摘要 |
Receptor molecules are anchored on a solid or fluid flat substrate, these being able to selectively bind other atoms or molecules. The substrate surface is then ellipsometrically measured in that the change of the state of polarization, undergone by the linearly polarized light with the reflection on the substrate, is acquired. Subsequently, the substrate with the receptor molecules anchored thereon, for coupling the atoms or molecules to be determined, are exposed to the latter, after which an ellipsometrical measurement is again effected. The changes in the state of polarization are compared to values evaluated by way of reference samples, after which a qualitative and quantitative determination of the coupled atoms or molecules is effected.
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