摘要 |
<p>PCT No. PCT/EP96/01263 Sec. 371 Date Oct. 3, 1997 Sec. 102(e) Date Oct. 3, 1997 PCT Filed Mar. 22, 1996 PCT Pub. No. WO96/31510 PCT Pub. Date Oct. 10, 19964-Amino-1H-pyrazolo[3,4-d]pyrimidine derivatives of formula I wherein the symbols are as defined in claim 1, and intermediates for their manufacture are described. The compounds of formula I inhibit especially the tyrosine kinase activity of the receptor for epidermal growth factor and can be used, for example, in the case of epidermal hyperproliferation (psoriasis) and as anti-tumor agents.</p> |