发明名称 |
METHODS FOR AMELIORATING ICTHYOSIFORM SKIN DISEASES |
摘要 |
The present invention relates to the discovery of a method to provide stabilized transglutaminase (1) enzyme, involucrin, and other molecules necessary for the assembly of the cell envelope to skin cells. Novel biological tools, prophylactics, therapeutics, cosmetics, and methods of use of the foregoing for study, prevention, and treatment of skin disorders are also disclosed. Further is disclosed a synthetic ceramide analog, called lipid Z and methods for its use and synthesis.
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申请公布号 |
WO0078937(A1) |
申请公布日期 |
2000.12.28 |
申请号 |
WO2000US17235 |
申请日期 |
2000.06.22 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, ASREPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES;STEINERT, PETER;MAREKOV, LYUBEN;NEMES, ZOLTAN |
发明人 |
STEINERT, PETER;MAREKOV, LYUBEN;NEMES, ZOLTAN |
分类号 |
A61K9/133;A61K38/00;A61P17/00;C12N9/10;(IPC1-7):C12N9/10;A61K38/46;C07C235/08;C07C235/28 |
主分类号 |
A61K9/133 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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