发明名称 BICYCLIC HETEROCYCLES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESSES FOR PREPARING THEM
摘要 The invention relates to bicyclic heterocycles of general formula (I), in which Ra to Rc, A to E and X are defined as in Claim No. 1, to their tautomers, their stereoisomers and their salts, especially their physiologically compatible salts having inorganic or organic acids or bases. The inventive bicyclic heterocycles comprise valuable pharmacological properties, especially an inhibitory effect on the signal transduction procured by tyrosine kinases. The invention also relates to the use of the inventive bicyclic heterocycles for treating illnesses, especially tumor diseases, diseases of the lung and of the respiratory tract, and relates to the production of the inventive compounds.
申请公布号 CA2375259(A1) 申请公布日期 2000.12.28
申请号 CA20002375259 申请日期 2000.06.16
申请人 BOEHRINGER INGELHEIM PHARMA KG 发明人 HIMMELSBACH, FRANK;JUNG, BIRGIT;BAUM, ANKE;SOLCA, FLAVIO;METZ, THOMAS;LANGKOPF, ELKE
分类号 A61K31/517;A61K31/5377;A61K31/541;A61K31/551;A61P1/00;A61P11/00;A61P35/00;C07D215/42;C07D215/54;C07D239/94;C07D401/12;C07D403/12;C07D405/12;C07D413/12 主分类号 A61K31/517
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