发明名称 |
Nucleotide sequences for gene regulation and methods of use thereof |
摘要 |
The invention provides nucleic acid sequences which regulate expression of a nucleotide sequence of interest. In particular, the invention provides nucleic acid sequences which regulate expression of a nucleotide sequence of interest in an age-related manner and/or in a liver-specific manner. The invention further provides methods of using the regulatory nucleic acid sequences provided herein for age-related and/or liver-specific expression of nucleotides seuqences of interest. The invention also provides host cells and transgenic non-human animals which harbor the regulatory nucleic acid sequences of the invention. The compositions and methods of the invention are useful in regulating expression of a nucleotide sequence of interest in an age-related and/or liver-specific manner. |
申请公布号 |
AU5328600(A) |
申请公布日期 |
2000.12.28 |
申请号 |
AU20000053286 |
申请日期 |
2000.06.06 |
申请人 |
REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
KOTOKU KURACHI;SUMIKO KURACHI |
分类号 |
C12N15/09;A61K31/7088;A61K38/00;A61K39/395;A61K48/00;A61P1/16;A61P3/10;A61P7/02;A61P9/10;A61P19/02;A61P19/10;A61P25/16;A61P25/28;A61P35/00;C07K14/47;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/64 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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