摘要 |
Methods and compositions are provided for preventing p53 mediated apoptosis in host. In the subject methods, an effective amount of an agent having hAPP anti-p53 apoptotic activity is administered to the host. The subject methods find use in the treatment of disease conditions associated with p-53 mediated apoptosis, particularly p53 mediated neuronal apoptosis, e.g., neurodegenerative diseases such as Alzheimer's Disease. |