发明名称 NOVEL ERYTHROMYCIN DERIVATIVES, PROCESS TO PREPARE THEM AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
摘要 The invention relates to the compounds (I): <IMAGE> in which, - either X and X' form C=O or C=NOR with R=H, heterocycle, alkyl, alkenyl, alkynyl, optionally substituted, or X represents a radical <IMAGE> R<a>, Rb representing H or hydrocarbon radical or forming a heterocycle with N or a 9-N, 11-O ring with A and X' = H, - Y and Y' have the same meaning as X and X', - B = H, OR4, R4 = H or forms a carbonate or a carbamate with A, - A forms a double bond with C, or - A = OR'4, R'4 = H or forms a carbonate with B <IMAGE> R2 = alk or CONH2, CONHCOR11 or CONHSO2R11, R11 = hydrocarbon up to 18 C, R3 = H, alkyl <IMAGE> Z = H or carboxylic acid residue, and their salts, their preparation and their application as medicaments.
申请公布号 HU218787(B) 申请公布日期 2000.12.28
申请号 HU19910003622 申请日期 1991.11.20
申请人 Hoechst Marion Roussel 发明人 AGOURIDAS, CONSTANTIN;BENEDETTI, YANNICK;CHANTOT, JEAN-FRANCOIS;DENIS, ALEXIS;FROMENTIN, CLAUDE;LE MARTRET, ODILE
分类号 A61K31/70;A61K31/7042;A61K31/7048;A61K31/7052;A61P31/00;A61P31/04;A61P31/12;C07H;C07H17/00;C07H17/08 主分类号 A61K31/70
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