发明名称 |
PROCESS FOR PRODUCING CREATINE AND CREATINE-MONOHYDRATE |
摘要 |
Prepn. of creatine or creatine monohydrate comprises reaction of the sodium or potassium salt of sarcosine with cyanamide in water or a mixture of water and organic solvent at 20-150 degrees C and at pH 7.0-14.0. Reaction temp. is 50-100 degrees C, pH = 9.0-10.0 and acid regulated, molar ratio cyanamide:sarcosinate salt is 1:4-4:1 (pref. 0.9:1-1.25:1), sarcosine salt being present as a 35-45 wt.% aq. soln. and the cyanamide as pref. 50 wt.% aq. soln. Pref. organic solvent is a 1-5C aliphatic alcohol. Reaction product is purified by and recrystallised from water. Dry creatine product is less than 1 wt.% and the monohydrate has approx. 12.1 wt.% water content. |
申请公布号 |
HU218820(B) |
申请公布日期 |
2000.12.28 |
申请号 |
HU19960001954 |
申请日期 |
1996.07.17 |
申请人 |
SKW Trostberg Aktiengesellschaft |
发明人 |
KROMMER, HELMUT;DR.WEISS, STEFAN |
分类号 |
C07C277/02;C07C277/06;C07C277/08;C07C279/14 |
主分类号 |
C07C277/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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