摘要 |
<p>A stabilized medicinal composition for oral administration which contains both 4-[[3-[p-(carboxyamidino)-phenyl]-2-oxo-5-oxazolidinyl]methyl]-1-piperazineacetic acid, 1-ethyl-, methyl ester, exhibiting GP IIb-IIIa receptor antagonism or a pharmaceutically acceptable salt thereof and an oily base; a process for the preparation of a stabilized medicinal composition for oral administration by combining an oily base with 4-[[3-[p-(carboxyamidino)phenyl]-2-oxo-5-oxazolidinyl]methyl]-1-piperazineacetic acid, 1-ethyl-, methyl ester or a pharmaceutically acceptable salt thereof; and a method for stabilizing a medicinal composition which comprises combining an oily base with 4-[[3-[p-(carboxyamidino)-phenyl]-2-oxo-5-oxazolidinyl]methyl]-1-piperazineacetic acid, 1-ethyl-, methyl ester or a pharmaceutically acceptable salt thereof.</p> |