发明名称 METHODS FOR PROFILING AND CLASSIFYING TISSUE USING A DATABASE THAT INCLUDES INDICES REPRESENTATIVE OF A TISSUE POPULATION
摘要 A sample of normal tissue specimens obtained from a subset of a population o f subjects with shared characteristics is profiled in order to generate a plurality of structural indices that correspond to statistically significant representations of characteristics of tissue associated with the population. The structural indices include cell density, matrix density, blood vessel density and layer thickness. Alternatively, the sample of normal tissue specimens obtained from the subset of the population of subjects with shared characteristics can also be profiled in order to generate a plurality of cel l function and/or mechanical indices that correspond to statistically significant representations of characteristics of tissue associated with the population. Structural, mechanical and/or cell function indices for a plurality of tissue populations are determined, and then stored in a databas e. The database information is then used to classify tissue specimens (e.g., human tissue specimens, animal tissue specimens, plant tissue specimens, foo d tissue specimens, or manufactured tissue specimens) provided by a user. In particular, a user measures parameters (e.g., structural, mechanical and/or cell function indices) associated with the user's tissue specimens and then compares this information to corresponding parameters for normal tissue in t he database in order to classify the user's tissue specimens as either normal o r abnormal.
申请公布号 CA2389220(A1) 申请公布日期 2000.12.28
申请号 CA20002389220 申请日期 2000.06.23
申请人 TISSUEINFORMATICS, INC. 发明人 JOHNSON, PETER C.
分类号 G01N33/48;C12Q1/68;G01N33/50;G01N33/68;G06F17/30;(IPC1-7):G01N33/48 主分类号 G01N33/48
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