发明名称 New vector for tissue-specific expression, useful for treating tumors, contains gene for e.g. a cytotoxin under control of tissue-specific promoter and enhancer
摘要 A vector for tissue-specific expression of a gene (I) that encodes a cytotoxin or prodrug-activating protein (II), comprising at least one tissue-specific enhancer, functionally linked to a tissue-specific promoter, and a coding sequence for (II), is new. An Independent claim is also included for a cell containing the novel vector.
申请公布号 DE19928342(A1) 申请公布日期 2000.12.28
申请号 DE19991028342 申请日期 1999.06.21
申请人 DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS 发明人 SCHADENDORF, DIRK;PASCHEN, ANNETTE
分类号 A61K31/711;A61K48/00;A61P35/00;C12N15/55;C12N15/86;(IPC1-7):C12N15/63;C12N15/861;C12N5/16 主分类号 A61K31/711
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