发明名称 |
New vector for tissue-specific expression, useful for treating tumors, contains gene for e.g. a cytotoxin under control of tissue-specific promoter and enhancer |
摘要 |
A vector for tissue-specific expression of a gene (I) that encodes a cytotoxin or prodrug-activating protein (II), comprising at least one tissue-specific enhancer, functionally linked to a tissue-specific promoter, and a coding sequence for (II), is new. An Independent claim is also included for a cell containing the novel vector.
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申请公布号 |
DE19928342(A1) |
申请公布日期 |
2000.12.28 |
申请号 |
DE19991028342 |
申请日期 |
1999.06.21 |
申请人 |
DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS |
发明人 |
SCHADENDORF, DIRK;PASCHEN, ANNETTE |
分类号 |
A61K31/711;A61K48/00;A61P35/00;C12N15/55;C12N15/86;(IPC1-7):C12N15/63;C12N15/861;C12N5/16 |
主分类号 |
A61K31/711 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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