SHANK PROTEINS AND METHODS OF USE THEREOF

摘要

Shank proteins and nucleotides encoding Shank proteins are provided. Also provided is a method for identifying a compound that modulates a cellular response mediated by Shank proteins. A method is further provided for identifying a compound that modulates cytoskeletal stability mediated by Shank proteins. A method is provided for identifying a compound that modulates synaptic receptor localization or synaptic receptor clustering, which are mediated by Shank proteins.