Disclosed herein are buffered flowable nasal sprays having a pH of between 4.0 and 5.0. They are primarily water and a citrate (or citrate/phosphate) buffer. They may also contain sodium chloride, thickeners, and/or preservatives. The preparations are able to maintain the aforesaid pH under conditions simulating a runny nose. Methods of using these preparations to inhibit the spread of rhinovirus and/or diseases caused by rhinovirus are also disclosed.
申请公布号
WO0076474(A1)
申请公布日期
2000.12.21
申请号
WO1999US30589
申请日期
1999.12.21
申请人
WISCONSIN ALUMNI RESEARCH FOUNDATION;GERN, JAMES, E.;MOSSER, ANNE, G.