METHODS FOR DETECTING MEMBRANE DERIVED CASPASE ACTIVITY AND MODULATORS THEREOF
摘要
Provided are methods for detecting membrane derived apoptotic activity. In one embodiment, the present invention provides methods for identifying membrane derived caspase activity. In other embodiments, drug discovery methods are provided for screening compounds that inhibit or enhance membrane derived caspase activity. In the various embodiments, heavy membrane fractions are utilized for the screening methodologies described herein.
申请公布号
WO0052194(A3)
申请公布日期
2000.12.21
申请号
WO2000US05889
申请日期
2000.03.06
申请人
IDUN PHARMACEUTICALS, INC.;FRITZ, LAWRENCE, C.;KREBS, JOSEPH, F.