发明名称 NOVEL FORMULATIONS COMPRISING LIPID-REGULATING AGENTS
摘要 The present invention is directed to a semi-solid formulation comprising a lipid-regulating agent. Said formulation is prepared by solubilizing said lipid-regulating agent in one or more liquid components to form a clear liquid solution, then solidifying said solution by adding one or more solid or semi-solid components to said solution to form a semi-solid formulation. Said formulation can melt or dissolve upon mixing with a bulk aqueous medium. The resulting formulation results in an increase in drug solubility and oral bioavailability, and an improved dissolution rate.
申请公布号 WO0076482(A1) 申请公布日期 2000.12.21
申请号 WO2000US15717 申请日期 2000.06.08
申请人 ABBOTT LABORATORIES 发明人 LIU, RONG, (RON);PAN, QINGHAI;HANSRANI, PAWAN
分类号 A61K9/48;A61K31/216;A61K31/22;A61K31/40;A61K45/00;A61K47/14;A61K47/22;A61K47/34;A61P3/04;A61P3/06;(IPC1-7):A61K9/48 主分类号 A61K9/48
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