发明名称 |
NOVEL FORMULATIONS COMPRISING LIPID-REGULATING AGENTS |
摘要 |
The present invention is directed to a semi-solid formulation comprising a lipid-regulating agent. Said formulation is prepared by solubilizing said lipid-regulating agent in one or more liquid components to form a clear liquid solution, then solidifying said solution by adding one or more solid or semi-solid components to said solution to form a semi-solid formulation. Said formulation can melt or dissolve upon mixing with a bulk aqueous medium. The resulting formulation results in an increase in drug solubility and oral bioavailability, and an improved dissolution rate.
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申请公布号 |
WO0076482(A1) |
申请公布日期 |
2000.12.21 |
申请号 |
WO2000US15717 |
申请日期 |
2000.06.08 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
LIU, RONG, (RON);PAN, QINGHAI;HANSRANI, PAWAN |
分类号 |
A61K9/48;A61K31/216;A61K31/22;A61K31/40;A61K45/00;A61K47/14;A61K47/22;A61K47/34;A61P3/04;A61P3/06;(IPC1-7):A61K9/48 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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