GENETIC POLYMORPHISM AND POLYMORPHIC PATTERN FOR ASSESSING DISEASE STATUS, AND COMPOSITIONS FOR USE THEREOF

摘要

The present invention provides methods for assessing disease status in an individual, which comprise determining the sequence at one or more polymorphic positions within the human genes encoding a protein involved in a physiologic pathway associated with a treatment regime. The invention also provides isolated nucleic acids encoding. These polymorphisms, nucleic acid probes that hybridize to polymorphic positions, kits for the prediction of disease status, and nucleic acid and peptide targets for use in identifying candidate drugs.