发明名称 |
ENANTIOMERS OF O-DESMETHYL VENLAFAXINE |
摘要 |
This invention provides pharmaceutically active enantiomers of the venlafaxine metabolite O-Desmethyl venlafaxine, R(-)-4-[2-(Dimethylamino-1-(1-hydroxycyclo-hexyl)ethyl]phenol or R(-)1-[2-(dimethylamino)-1-(4-hydroxyphenyl)-ethyl]cyclo-hexanol, and S(+)-1-[2-(Dimethylamino)-1-(4-hydroxyphenyl)ethyl]-cyclohexanol or S(+)-4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol, or one or more pharmaceutically acceptable salts or salt hydrates thereof, as well as pharmaceutical compositions utilizing these enantiomers and methods of using the enantiomers to treat, inhibit or control central nervous system disorders.
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申请公布号 |
WO0076955(A1) |
申请公布日期 |
2000.12.21 |
申请号 |
WO2000US16388 |
申请日期 |
2000.06.14 |
申请人 |
AMERICAN HOME PRODUCTS CORPORATION |
发明人 |
YARDLEY, JOHN, PATRICK;ASSELIN, ANDRE, ALFRED |
分类号 |
A61K31/137;C07C215/52;(IPC1-7):C07C215/52;A61K31/135;A61P25/24 |
主分类号 |
A61K31/137 |
代理机构 |
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主权项 |
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地址 |
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