发明名称 |
METHOD OF INHIBITING AMYLOID PROTEIN AGGREGATION AND IMAGINGAMYLOID DEPOSITS USING ISOINDOLINE DERIVATIVES |
摘要 |
<p>The present invention provides a method of treating Alzheimer's disease usin g a novel compound of formula (I), wherein X is phenyl or substituted phenyl; Y is phenyl, substituted phenyl, pyridyl, or substituted pyridyl. Also provide d is a method of inhibiting the aggregation of amyloid proteins using a compou nd of formula (I) and a method of imaging amyloid deposits using isoindoline derivatives.</p> |
申请公布号 |
CA2373394(A1) |
申请公布日期 |
2000.12.21 |
申请号 |
CA20002373394 |
申请日期 |
2000.05.31 |
申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
LAI, YINGJIE;SAKKAB, ANNETTE THERESA;WALKER, LARY CRASWELL;AUGELLI-SZAFRAN, CORINNE ELIZABETH |
分类号 |
A61K31/4035;A61K31/4178;A61K49/06;A61K51/04;A61P25/28;A61P43/00;C07D209/44;C07D401/12;C07D403/12;(IPC1-7):C07D209/44;A61K31/403 |
主分类号 |
A61K31/4035 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|