发明名称 |
ENZYMATIC PREPARATION OF PHOSPHOLIPIDS IN AQUEOUS MEDIA |
摘要 |
Methods of conducting phospholipase-catalyzed transesterification or hydrolysis of phospholipids present in aqueous liposomal suspensions, in the absence of detergents and organic solvents, are described. The method, which employs a water/solid particle interface, gives high conversions, particularly when the solid particle is silica gel having a small particle size and is present at a level at least four times the weight of the reacting lipid. The reaction is useful for the preparation of a variety of differently substituted phospholipids, as well as diacyl glycerols and ceramides. |
申请公布号 |
WO0077183(A1) |
申请公布日期 |
2000.12.21 |
申请号 |
WO2000IL00350 |
申请日期 |
2000.06.15 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW;BARENHOLZ, YECHEZKEL;AMSELEM, SHIMON |
发明人 |
BARENHOLZ, YECHEZKEL;AMSELEM, SHIMON |
分类号 |
C12N9/16;C12N9/18;C12P9/00;C12P13/00 |
主分类号 |
C12N9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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