| 摘要 |
The invention relates to derivatives of 4'-demycarosyl-8a-aza-8a-homotylosin of formula (I) wherein R represents CHO, CH(OCH3)2) or CH2N[CH2(C6H5)]2, R<1> represents H or C1-C3 acyl, R<2> represents OR<6> and R<6> represents H or C1-C3 acyl, R<3> represents H or R<2> and R<3> together represent =O, R<4> represents OH, R<5> represents H or R<4> and R<5> together represent =O, and to a process for the preparation thereof. Novel derivatives show antibacterial action and may also be used as intermediates for preparing novel 17-membered azalide antibiotics.
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