RETRO-INVERSO PEPTIDES DERIVED FROM LEUKEMIA INHIBITORY FACTOR
摘要
Retro-inverso peptides derived from leukemia inhibitory factor (LIF) having between 18 and about 40 amino acids and including the sequence shown in SEQ ID NO: 1. These peptides have the same activity as native LIF and also have neurotrophic activity. Because of the D-amino acid linkage in the peptides, they are less susceptible to proteolytic degradation <i>in vivo</i>.
申请公布号
WO0077029(A1)
申请公布日期
2000.12.21
申请号
WO2000US16760
申请日期
2000.06.16
申请人
MYELOS CORPORATION;WRIGHT, DAVID, E.;PARKS, D., ELLIOT