Reporter molecules and methods for assaying the lipidation status of a cell

摘要

The invention provides means and methods for determining the capability of an entity to interfere at least in part with the distribution of (part of) a reporter molecule in a cell. Said entity may be used to alter at least in part the function of a cellular proteinaceous molecule. Said methods may be used for instance for drug discovery and the phenotypic characterisation of cells, preferably patient cells. Phenotypic charaterisation of a cell includes for example determining the sensitivity of a cell for a specific drug. Said entity may be used for the preparation of a medicament.