| 摘要 |
The invention relates to the use of human homologues of <i>Drosophila</i> Suppressor of deltex (h-SDRP) in the form of nucleic acids, proteins and antibodies in diagnosis and therapy. The h-SDRP nucleic acid and amino acid sequences and antibodies thereto may be used according to the invention for the detection and quantitation of h-SDRP mRNA and protein, to study the expression thereof, to produce h-SDRP proteins, fragments and other derivatives or analogues for use in the study, assay and manipulation of differentiation and other physiological processes in which <i>Drosophila</i> Su(dx) is postulated to be involved, e.g. diseases of cell fate and abnormal differentiation and cell proliferation. |
