摘要 |
Preventive and/or therapeutic drugs for periodontal diseases containing as the active ingredient compounds of general formula (1) or salts thereof and being capable of preventing and/or treating effectively various periodontal diseases such as periodontitis, wherein R<1> is hydrogen or the like; R<2> is hydrogen, lower alkyl, or the like; R<3> is hydrogen, carboxyl, or the like; R<4> is hydrogen, halogeno, or the like; n is a number of 0 to 4; A is C1-C4 alkylene which may be substituted with one or two members selected from among hydroxyalkyl, carboxyl, and alkoxycarbonyl, or the like, X is a single bond, oxygen, or the like; and Y is an optionally substituted, saturated or unsaturated, five- or six-membered heterocyclic group or the like. |