发明名称 PROCESS FOR THE PREPARATION OF ERGOLINE DERIVATIVES
摘要 The invention provides a process for the preparation of ergoline derivatives of the formula I <IMAGE> I the process comprising reacting an ergoline amide of the formula II with an isocyanate of formula III <IMAGE> in presence of a metal catalyst and of a phosphorus compound. The compounds of the formula I are useful antiprolactinic and antiparkinson agents.
申请公布号 KR100274102(B1) 申请公布日期 2000.12.15
申请号 KR19937003386 申请日期 1993.11.10
申请人 PHARMACIA & UPJOHN S.P.A 发明人 CANDIANI, ILARIA;CABRI, WALTER;BEDESCHI, ANGELO;ZARINI, FRANCO
分类号 A61K31/48;A61P5/08;A61P25/16;C07D457/06 主分类号 A61K31/48
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