NOVEL 6-PHENYLPURINE 9- beta -D-RIBONUCLEOSIDES WITH ANTINEOPLASTIC ACTIVITY, THEIR USE FOR PREPARING PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL PREPARATIONS CONTAINING SUCH COMPOUNDS

摘要

Novel 6-phenylpurine 9- beta -D-ribonucleosides with antineoplastic activity of general formula (I), wherein R<1> is H, methyl, fluoro, chloro or alkoxy (C1-C2) group, R<2> is H, methyl or fluoro group, and R<3> is H, fluoro or methoxy group. Pharmaceutical compositions containing the compounds of the invention as active components are also described. Further the use of compounds of general formula (I) according to Claim 1, or their combinations, for preparing pharmaceutical compositions for the treatment of cancer and leukemia is described.