COMPOSITION AND METHOD FOR THE TREATMENT OF ENDOTOXIC SHOCK AND INFLAMMATORY AND AUTOIMMUNE DISEASES IN MAMMALS

摘要

The invention relates to the utilization of therapeutic agents inhibiting th e production of tumoral necrosis factor (TNF) and interleukin 6 (IL-6), which induce high levels of interleukin 4 (IL-4), in the treatment of endotoxic shock and inflammatory and autoimmune diseases in mammals. Said agents are t he vasoactive intestinal peptide (VIP), the pituitary adenylate cyclase- activating peptide (PACAP) and their corresponding fragments and derivatives .