MICROENCAPSULATED AND CONTROLLED-RELEASE HERBAL FORMULATIONS

摘要

There is provided an orally-administrable formulation for the controlled release or stable storage of a granulated herb, comprising a granulated herb and at least one carrier, adjuvant or excipient therefor. Preferably, the formulation is characterized in that the total in vitro dissolution time of said formulation required for release of 75 % of the active ingredients available from the formulation is between about 4 and about 18 hours, as determined by the U.S.P. XXIII paddle method at a paddle speed of 150 rpm, using simulated intestinal fluid without the digestive enzymes normally found in intestinal fluid, containing 0.1 % w/w sodium dodecyl sulfate (SDS), at pH 6.8, and a temperature of 37 DEG C. A process for the preparation of such formulation is also provided.