发明名称 |
INHIBITORS OF SERINE PROTEASE ACTIVITY, METHODS AND COMPOSITIONS FOR TREATMENT OF NITRIC OXIDE-INDUCED CLINICAL CONDITIONS |
摘要 |
A novel method of treating and preventing diseases is provided. In particular, compositions and methods of blocking diseases associated with aberrant levels of nitric oxide and facilitated by a serine proteolytic (SP) activity are disclosed, which consist of administering to a subject a therapeutically effective amount of a compound having a serine protease inhibitory activity. Among effective compounds are alpha 1-antitrypsin and synthetic drugs mimicking some or all of the actions of alpha 1-antitrypsin.
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申请公布号 |
WO0051623(A3) |
申请公布日期 |
2000.12.14 |
申请号 |
WO2000US05556 |
申请日期 |
2000.03.03 |
申请人 |
THE TRUSTEES OF UNIVERSITY TECHNOLOGY CORPORATION |
发明人 |
SHAPIRO, LELAND |
分类号 |
A61K38/08;A61K38/55;A61K38/57;(IPC1-7):A61K38/08;A61P35/00;A61P37/00;A61P25/00;A61P31/00 |
主分类号 |
A61K38/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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