| 发明名称 |
NOVEL REAGENTS FOR DETECTION AND PURIFICATION OF ANTIBODY FRAGMENTS |
| 摘要 |
An isolated B1 domain polypeptide of bacterial Protein G which binds a Fab fragment of an IgG but substantially does not bind an Fc fragment of an IgG. Methods for the detection and purification of IgG Fc antibody fragments and Fab antibody fragments using the isolated GB1 domain polypeptides are also disclosed. |
| 申请公布号 |
WO0074728(A1) |
申请公布日期 |
2000.12.14 |
| 申请号 |
WO2000US15366 |
申请日期 |
2000.06.02 |
| 申请人 |
DUKE UNIVERSITY |
发明人 |
HELLINGA, HOMME, W.;SLOAN, DAVID, J. |
| 分类号 |
C07K14/31;C07K14/315;C07K16/06;(IPC1-7):A61K51/00;A61K7/035;A61K39/10;G01N33/53;G01N33/569;G01N33/563;C12Q1/14;C12P21/06;C12N1/20;C12N5/06 |
主分类号 |
C07K14/31 |
| 代理机构 |
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代理人 |
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