NOVEL METHOD FOR PREPARING OPTICALLY ACTIVE ALPHA-AMINONITRILES
摘要
<p>The invention concerns a novel method for preparing optically active alpha -aminonitriles of formula (I) by enantioselective hydrocyanation using a hydrocyanation agent, in the presence of a chiral or chirality inducing metal complex acting as catalyst, of ketimines of formula (II) wherein the radicals R1 and R2 and T are such as defined in the description. The invention also concerns the use of alpha -aminonitriles of formula (I) as synthesis intermediates of optically active organic compounds.</p>
申请公布号
WO0075104(A1)
申请公布日期
2000.12.14
申请号
WO2000FR01597
申请日期
2000.06.09
申请人
AVENTIS CROPSCIENCE SA;BYRNE, JANICE;CHAVAROT, MURIELLE;CHAVANT, PIERRE-YVES;VALLEE, YANNICK;HENRYON, VIVIEN
发明人
BYRNE, JANICE;CHAVAROT, MURIELLE;CHAVANT, PIERRE-YVES;VALLEE, YANNICK;HENRYON, VIVIEN