| 摘要 |
Pharmaceutical compositions incorporate aryl substituted olefinic amine compounds. Representative compounds are (2S)-(4E)-N-methyl-5-[3-(5-isopropoxy-1-oxopyridin)yl)]-4-penten-2-amine, (3E)-N-methyl-4-(3-(1-oxopyridin)yl)-3-buten-1-amine, (4E)-N-methyl-5-(3-(1-oxopyridin)yl)-4-penten-2-amine, (4E)-N-methyl-5-(3-(5-((carboxymethyl)oxy)pyridin)yl)-4-penten-2-amine, (3E)-N-methyl-4-[3-(5-nitro-6-aminopyridin)yl]-3-buten-1-amine, (3E)-N-methyl-4-[3-(5-(N-benzylcarboxamido)pyridin)yl]-3-buten-1-amine(4E)-N-methyl-5-[5-(2-aminopyrimidin)yl]-4-penten-2-amine, (4E)-N-methyl-5-(3-(5-aminopyridin)yl)-4-penten-2-amine (3E)-N-methyl-4-(3-(5-isobutoxypyridin)yl)-3-buten-1-amine, (3E)-N-methyl-4-(3-(5-ethylthiopyridin)yl)-3-buten-1-amine, (4E)-N-methyl-5-(3-(5-trifluoromethylpyridin)yl)-4-penten-2-amine, (4E)-5-(3-(5-isopropoxypyridin)yl)-4-penten-2-amine, and (4E)-5-(3-(5-isopropoxypyridin)yl)-4-penten-2-amine.
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| 申请人 |
TARGACEPT, INC.;DULL, MAURICE, DULL;MILLER, CRAIG, HARRISON;CALDWELL, WILLIAM, SCOTT;LYNM, DWO;BHATTI, BALWINDER, SINGH;SCHMITT, JEFFREY, DANIEL;BYRD, GARY, DWIGHT;HADIMANI, SRISHAILKUMAR, BASAWANNAPPA |
发明人 |
DULL, MAURICE, DULL;MILLER, CRAIG, HARRISON;CALDWELL, WILLIAM, SCOTT;LYNM, DWO;BHATTI, BALWINDER, SINGH;SCHMITT, JEFFREY, DANIEL;BYRD, GARY, DWIGHT;HADIMANI, SRISHAILKUMAR, BASAWANNAPPA |
