发明名称 REMEDIES FOR BRAIN INFARCTION
摘要 <p>This invention is to provide remedies for cerebral infarction which contain as an active ingredient a compound having mGluR1 antagonism, pharmaceutical compositions which are remedies for cerebral infarction at the acute stage, pharmaceutical compositions which contain as an active ingredient a compound having selective mGluR1 antagonism, and pharmaceutical compositions wherein the compound having selective mGluR1 antagonism is 6-amino-N-cyclohexyl-N,3-dimethylthiazolo 3,2-a­benzoimidazole-2-carboxamide dihydrochloride. Means for resolution Since a compound having mGluR1 antagonism showed an effect of reducing infarction volume in a rat cerebral infarction model, it was found out that mGluR1 antagonists are useful in preventing and treating cerebral infarction.</p>
申请公布号 EP1059090(A1) 申请公布日期 2000.12.13
申请号 EP19990906548 申请日期 1999.03.02
申请人 ASTELLAS PHARMA INC. 发明人 OKADA, MASAMICHI;TAKAHASHI, MASAYASU;HAYASHIBE, SATOSHI
分类号 A61K45/00;A61K31/00;A61K31/425;A61K31/428;A61K31/429;(IPC1-7):A61K45/00 主分类号 A61K45/00
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