发明名称 |
Compositions for controlling bacterial colonization |
摘要 |
A composition for controlling bacterial growth/colonization is provided. The composition comprises a selected enzyme, a selected anchor molecule coupled to the enzyme to form an enzyme-anchor complex, with the anchor being capable of attaching to a substrate proximal to a bacterial colony. The attachment to the substrate permits prolonged retention time of the enzyme-anchor complex where the bacterial colony is present to increase the effectiveness of the complex. The invention is also for a method of controlling colonization of bacterial plaque in the oral cavity, as well as a method of forming a composition for controlling the proliferation of bacterial colonies in the oral cavity.
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申请公布号 |
US6159447(A) |
申请公布日期 |
2000.12.12 |
申请号 |
US19990249674 |
申请日期 |
1999.02.12 |
申请人 |
PHARMACAL BIOTECHNOLOGIES, LLC |
发明人 |
BUDNY, JOHN A.;BUDNY, MATTHEW J. |
分类号 |
A61K47/24;A61K8/44;A61K8/60;A61K8/64;A61K8/66;A61K8/73;A61K8/86;A61K38/46;A61K38/47;A61K47/26;A61K47/32;A61K47/42;A61K47/48;A61P1/02;A61Q11/00;(IPC1-7):A61K7/16;A61K7/28;A61K38/00;A61K31/70 |
主分类号 |
A61K47/24 |
代理机构 |
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主权项 |
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地址 |
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