发明名称 |
Lymphocyte chemoattractant factor |
摘要 |
Purified DNA encoding LCF and the recombinant proteins expressed from such DNA are disclosed. In addition, the invention provides methods for suppressing an LCF-CD4 interaction and screening candidate LCF agonists or antagonists. The invention also provides compositions and methods useful for stimulating proliferation of CD4+ T-cells in a mammal.
|
申请公布号 |
US6159463(A) |
申请公布日期 |
2000.12.12 |
申请号 |
US19950581103 |
申请日期 |
1995.12.29 |
申请人 |
RESEARCH CORPORATION TECHNOLOGIES, INC. |
发明人 |
CENTER, DAVID M.;CRUIKSHANK, WILLIAM W.;KORNFELD, HARDY |
分类号 |
G01N33/53;A61K38/00;A61K38/20;A61K39/395;A61P31/12;C07K14/54;C07K14/73;C07K16/22;C07K16/24;C12N1/21;C12N5/00;C12N5/10;C12N15/02;C12N15/09;C12N15/19;C12P21/02;C12P21/08;C12R1/19;C12R1/91;(IPC1-7):A61K45/00 |
主分类号 |
G01N33/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|