INTRAORAL DISINTEGRATION-TYPE TABLET CONTAINING VITAMIN K

摘要

PROBLEM TO BE SOLVED: To provide an intraoral disintegration-type tablet containing vitamin K and to provide a method for producing the same tablet. SOLUTION: This tablet is prepared by tabletting wet powder comprising vitamin K adsorbed by crystalline cellulose, at least one of saccharides and a solvent. The tablet is produced by adsorbing vitamin K with crystalline cellulose, by granulating them using a mixture of water with an alcohol and then by mixing the resultant particles with at least one of saccharides, followed by humidifying them with water and/or an alcohol and tabletting them. The resultant tablet disintegrates within 30 s in the mouth.