发明名称 |
Solid phase immunoassay to detect inhibitors of proteolytic enzymes |
摘要 |
PCT No. PCT/EP95/00867 Sec. 371 Date Sep. 23, 1996 Sec. 102(e) Date Sep. 23, 1996 PCT Filed Mar. 9, 1995 PCT Pub. No. WO95/26505 PCT Pub. Date Oct. 5, 1995Solid phase immunoassay for detecting specific inhibitors of proteolytic enzymes in biological fluids, which comprises: a) contacting a tubulin peptide covalently linked to a support with a solution containing a proteolytic activity together with a protease inhibitor, b) detecting the inhibitor activity against the selected proteases by contacting the support with a solution containing a labelled monoclonal antibody which specifically recognises the free end of the tubulin peptide linked to the support.
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申请公布号 |
US6159746(A) |
申请公布日期 |
2000.12.12 |
申请号 |
US19960714159 |
申请日期 |
1996.09.23 |
申请人 |
GRUPPO LEPETIT S.P.A. |
发明人 |
ISLAM, KHALID;CARRANO, LUCIA;DENARO, MAURIZIO |
分类号 |
G01N33/53;C07K14/00;C07K14/47;C12P21/08;C12Q1/37;G01N33/573;G01N33/577;G01N33/68;(IPC1-7):G01N33/533 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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