发明名称 Keratan sulfate oligosaccharide fraction and pharmaceutical containing the same
摘要 A keratan sulfate oligosaccharide which comprises from two to five sugar units and has sulfated N-acetylglucosamine at the reducing end and in a molecule of which at least two hydroxyl groups are sulfated, preferably, which contains at least disaccharide represented by the formula Gal(6S)-GlcNAc(6S) (in the formula, Gal, GlcN, Ac, and 6S represent a galactose, a glucosamine, an acetyl group, and a 6-O-sulfate ester, respectively) as a constitutional ingredient, and/or pharmaceutically acceptable salt thereof are used as active ingredients of anti-inflammatory agents, antiallergic agents, immunomodulators, cell differentiation inducers, and apoptosis inducers.
申请公布号 US6159954(A) 申请公布日期 2000.12.12
申请号 US19990317380 申请日期 1999.05.24
申请人 SEIKAGAKU CORPORATION 发明人 MARUYAMA, HIROSHI;MORIKAWA, KIYOSHI;TAWADA, AKIRA;MIYAUCHI, SATOSHI;YOSHIDA, KEIICHI;ASARI, AKIRA
分类号 A61K31/737;C07H11/00;C07H13/04;C08B37/00;C12P19/26;(IPC1-7):A61K31/70 主分类号 A61K31/737
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