发明名称 GROEL MUTEINS WITH IMPROVED STABILITY
摘要 A GroEL chaperone polypeptide, or homologue thereof, or fragment thereof having protein refolding activity, comprising one or more amino acid modifications at any one of amino acid residues (207, 212, 217, 223, 233, 26 7, 271, 294, 305, 308 and 326) of the GroEL amino acid sequence shown as SEQ I. D. No. 1 or their equivalent positions in other homologous chaperone polypeptid es is provided.
申请公布号 CA2375095(A1) 申请公布日期 2000.12.07
申请号 CA20002375095 申请日期 2000.05.26
申请人 MEDICAL RESEARCH COUNCIL 发明人 BUCKLE, ASHLEY MAURICE;FERSHT, ALAN
分类号 C12N15/09;A61K31/7088;A61K38/00;A61K39/395;A61K48/00;A61P25/28;C07K14/245;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/31;C12P21/02;(IPC1-7):C12N15/31;C07K16/12;A61K38/16;C12N15/62 主分类号 C12N15/09
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