| 发明名称 |
METHODS AND COMPOSITIONS FOR LOWERING THE LEVEL OF TUMOR NECROSIS FACTOR (TNF) IN THE TNF-ASSOCIATED DISORDERS |
| 摘要 |
The present invention provides recombinant adeno-associated virus (rAAV) vectors encoding a tumor necrosis factor (TNF) antagonist and methods using these vectors to reduce levels of TNF in a mammal. The invention also provides methods of using these rAAV vectors in palliating TNF-associated disorders.
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| 申请公布号 |
WO0073481(A1) |
申请公布日期 |
2000.12.07 |
| 申请号 |
WO2000US14586 |
申请日期 |
2000.05.26 |
| 申请人 |
TARGETED GENETICS CORPORATION;BURSTEIN, HAIM;STEPAN, ANTHONY, M. |
发明人 |
BURSTEIN, HAIM;STEPAN, ANTHONY, M. |
| 分类号 |
C12N15/09;A61K35/76;A61K45/00;A61K48/00;A61P19/02;A61P29/00;C07K14/715;C12N5/10;C12N7/00;C12N15/12;C12N15/864;(IPC1-7):C12N15/864;C12N15/62;C07K19/00 |
主分类号 |
C12N15/09 |
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