2-ARYLPURINE-9-ACETAMIDE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES OF THE DERIVATIVES

摘要

2-Arylpurine-9-acetamide derivatives represented by general formula (I) or pharmaceutically acceptable acid addition salts thereof, which selectively act on BZ omega 3 receptor and are useful as therapeutic and preventive drugs for central diseases such as anxiety-related diseases, depression and epilepsy. In said formula (I) R<1> is lower alkyl, cycloalkyl, cycloalkylated lower alkyl, or the like; R<2> is lower alkyl, substituted or unsubstituted phenyl, or the like; R<3> is hydrogen or the like; R<4> is hydrogen, lower alkyl, cycloalkyl, halogeno, lower alkoxy, or the like; A is substituted or unsubstituted phenyl or the like; W is hydrogen, lower alkyl, halogeno, lower alkoxy, lower alkylthio, lower alkanoyl, or the like.