发明名称 |
VIRUS IMMUNOLOGIC DETERMINANTS |
摘要 |
Polypeptides of virus that bind to virus antibodies or block binding of virus to mammalian cells are described. Derivatives of peptides can be less immunogenic, enhance binding to cells, render a virus tissue specific and so on. The nucleic acid sequence encoding those derivatives can be incorporated into a capsid encoding sequence to enable a virus to express such a derivative and be less immunogenic, have enhanced transduction efficiency or be tissue specific.
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申请公布号 |
WO0073316(A2) |
申请公布日期 |
2000.12.07 |
申请号 |
WO2000US14466 |
申请日期 |
2000.05.26 |
申请人 |
CELL GENESYS, INC.;PATEL, SALIL;MCARTHUR, JAMES |
发明人 |
PATEL, SALIL;MCARTHUR, JAMES |
分类号 |
C12N15/09;A61K38/00;A61P43/00;C07K14/075;C07K14/15;C12N7/00;C12N15/864;(IPC1-7):C07H/ |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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