SYNERGISTIC COMBINATIONS OF GUANOSINE ANALOG REVERSE TRANSCRIPTASE INHIBITORS AND INOSINE MONOPHOSPHATE DEHYDROGENESE INHIBITORS AND USES THEREFOR

摘要

Synergistic combinations of guanosine nucleoside analog reverse transcriptase inhibitors such as abacavir with inosine monophosphate dehydrogenase inhibitors such as mycophenolates, pharmaceutical compositions comprising such combinations, and therapeutic methods comprising administering the synergistic combinations to subjects in need thereof, for treating a viral infection, such as an HIV-1 infection.