发明名称 |
PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMENE DERIVATIVE |
摘要 |
<p>A process for producing a compound of the formula (II): <CHEM> wherein R<1>, R<2>, R<3> and R<4> are each independently e.g. hydrogen, alkyl or alkoxy, R<5> is alkyl or alkoxyalkyl, A is 0 or S, Ar is aryl, * represents the position of an asymmetric carbon atom and the compound is the (R) or (S) isomer and Q is an optical resolution reagent, comprising isolating the compound as crystals from a solution or suspension containing the compound of the formula (II) wherein * represents that the compound is the (R) or (S) isomer or a mixture thereof and the other symbols are the same as above.</p> |
申请公布号 |
EP1057824(A1) |
申请公布日期 |
2000.12.06 |
申请号 |
EP19990902911 |
申请日期 |
1999.02.16 |
申请人 |
SHIONOGI & CO., LTD. |
发明人 |
KONOIKE, TOSHIRO;YORIFUJI, TADAHIKO;SHINOMOTO, SHOJI;IDE, YUTAKA;OHYA, TAKASHI;MATSUMURA, KEN-ICHI |
分类号 |
C07D311/30;C07D407/04;(IPC1-7):C07D311/30;C07D335/06;C07B57/00;A61K31/38;A61K31/36;A61K31/35;C07D409/04 |
主分类号 |
C07D311/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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