发明名称 Process for preparing loracarbef monohydrate
摘要 <p>The invention is directed to a crystalline anhydrate solvate of loracarbef, and also is directed to a process for preparing a crystalline monohydrate form of the compound of formula (I) <CHEM> which comprises drying a crystalline isopropanolate form of the compound of formula (I) at a temperature of from about 50 DEG C to about 100 DEG C to provide a crystalline anhydrate form of the compound of formula (I); and exposing the crystalline anhydrate form of the compound of formula (I) to a relative humidity of from about 90 to about 100%.</p>
申请公布号 IL117228(A) 申请公布日期 2000.12.06
申请号 IL19960117228 申请日期 1996.02.22
申请人 ELI LILLY AND COMPANY 发明人
分类号 C07D471/04;C07D463/00;C07D463/22;(IPC1-7):C07D463/06;A61P31/04 主分类号 C07D471/04
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